Did God Give You Kidney Stones?
DNA is often given supernatural attributes, and its uniqueness is often hard to separate from God as an origin. I have witnessed this understanding many times over the years. Here are some examples:
Mike Matthews, the editor in chief of Answers in Genesis, stated in a 2003 article:
"Unlike the atheists, creationists see the genetic code as astonishing evidence for a Designer, who created a marvelously complex, efficient 'information system' for encoding life. The only reasonable explanation for all the information in DNA is that a Designer put all the information in the original genes—e.g. the 'kinds' that He made during the six days of Creation" [1].
Mike Matthews seems unable to resist personifying DNA and nature. The marvelous complexity that surpasses his comprehension compels his personification and assumption that there are no alternatives to the perceived superior Intelligence. It is unscientific to assume this without trying alternative options!
Biochemist Dr. Duane Gish, former vice president of the Institute of Creation Research, seems to fall into the same personification trap in this quote by Answers in Genesis in 2003:
"The genetics are so incredibly complex and can be so marvelously interrelated that it's absolutely going to demand an intelligent source. The idea that all of this could have come about by random accidents, genetic errors, and so forth is just simply beyond comprehension" [1].
In 2014, Lee Strobel wrote in Focus on the Family:
"The six feet of DNA coiled inside every one of our body's one hundred trillion cells contain a four-letter chemical alphabet that spells out precise assembly instructions for all the proteins from which our bodies are made. Cambridge-educated Stephen Meyer demonstrated that no hypothesis has come close to explaining how information got into biological matter by naturalistic means. On the contrary, he said that whenever we find a sequential arrangement that's complex and corresponds to an independent pattern or function such as books and computer code, this kind of information is always the product of intelligence" [2].
It is amazing to see gargantuan amounts of DNA and cells wrapped up in such a small space. Coupled with over-analogized genetic codes and letters, the amazingness of DNA offers the illusion of a divine message. The amazingness is so powerful that it is hard to stop assuming that divinity is the only choice of origin.
That general perception has not abated in the last 10 years, as a freelance writer, Valerie Schultz, wrote in 2018 in America--The Jesuit Review:
"Because your DNA is yours and yours alone. Your DNA is like a blueprint of your soul, which is another sacred thing that is not like anyone else's in the world. Your DNA traces your history and your future, because it determines who you came from and who you will create. It is a miracle of life. God is in the microscopic details, in the meeting of egg and sperm in the particular way that could only have led to you. DNA is a kind of holy ground. I am not scientifically inclined, but if I were, I can imagine that the wonder of each strand of DNA, of the intricacy of the 23 pairs of chromosomes that equals only me, would point to the existence of God. Could something as astounding as our DNA have come from anywhere else but a loving Creator? 'Before I formed you in the womb," says the God of Jeremiah, 'I knew you'" [3].
Even professionals as prestigious as Francis Collins have been on the bandwagon. As he is the Human Genome Project leader that determined the base pairs of DNA, Collins has explained DNA as "our own instruction book, previously known only to God." Reportedly, he convinced Bill Clinton, a former U.S. president who is quoted as saying, "Today, we are learning the language in which God created life." With his prestige and influence on the public, Collins could have "done science a disservice," according to Katrin Weigmann in a U.S. National Library of Medicine article [4].
If DNA is the product of an Intelligent Designer/Creator, the design is significantly flawed. The breakdown of DNA converts nucleic acids into uric acid that must be daily excreted in the form of sodium urate, putting us at risk of having gout, kidney stones, cardiovascular disease, hypertension, obesity, metabolic syndrome, diabetes, and cardiorenal disease [5].
Due to limited solubility or breakability of uric acid and calcium oxalate, they can over-accumulate in the blood and urine, concentrating and precipitating in clumps that are acutely painful to pass through the ureter, which is the duct from the kidney to the bladder (McMurry et al., 2017) [6].
The Creator, said to be perfect, made a mistake when forming your "inmost being," knitting you together in your mother's womb, and having you be "fearfully and wonderfully made" (See Psalm 139:13-14). This big mistake is seen in postmenopausal women who are at high risk of kidney stones. He made a mistake by not making us more compatible with rhubarb, spinach, blueberries, and chocolate, of which their high intake of dietary oxalates put us at risk. Due to the Creator's refusal to improve nucleic acid/purine metabolism, we must use a drug called allopurinol to diminish sodium urate by blocking an enzyme called xanthine oxidase that helps make the uric acid (McMurry et al., 2017) [6].
A mutation in our history caused us not to inherit the uricase enzyme that converts uric acid into more soluble stuff (particularly allantoin) to pass benignly through the body. The uricase mutation took place roughly 15 million years ago during the Miocene's global cooling and food shortage that forced early primates to change survival strategies. Uric acid has been suggested to be a threat indicator bestowed upon us by the RNA world [7].
The uricase gene lost its useful purpose in two primate lineages during the mid-Miocene period, thereby transferring a higher serum uric acid to humans, great apes, and lesser apes. It is harder to regulate in us than in other mammals [8].
The uricase deactivation is said to have occurred gradually, beginning with mutations in the 5' mark of the RNA polymerase end of the transcription initiation site and then mutating again in the codon 33 of exon 2 in the ancestral ape. A different mutation occurred in codon 18 of exon 2 in the ancestral ape of lesser apes roughly 9.8 million years ago. Uricase mutations could have occurred independently in new world monkeys since uricase seems to be diminished in old world monkeys compared to many other mammals. There is an overall selection pressure targeting uricase disappearance [8] [9].
Scientists have proposed that uricase mutations exploited the fuel sources of fruit fructose to improve survival, with Europe as the spot where organisms found refuge against inimical conditions, thereby supporting the Back to Africa Hypothesis but still not ignoring other possible theories for this mutation [10].
Adenosine triphosphate compounds (used for energy) and cAMP intracellular signaling molecules were carried over to current lifetimes from the remnants of the RNA world consisting of life's earliest forms. It is essential to note this since hyperuricemia (elevated uric acid levels in the blood) are associated with ATP depletion and energy troubles [11].
Dying cells produce uric acid that has been demonstrated to cause immune system inflammation. Uric acid is an immunity enhancement that switches on dendritic and T cells specially found in tissues and skin. Uric acid will increase during fuel exhaustion and rapid turnover of proteins during starvation and hibernation to prompt the organism to forage for food. Uric acid is also associated with preeclampsia that endangers pregnant women with high blood pressure, swelling, and proteinuria [7].
I cannot expect these design blunders to convince everyone that there is no Designer/Creator. This at least shows me that the Designer/Creator is not perfect nor all-powerful if He exists. The Designer/Creator is different from what popular Biblical doctrines and interpretations portray. It is hardly worthy of praise. I reckon that a standard Christian comeback would be to say that sin caused this flaw, which flies in the face of being "fearfully and wonderfully made."
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All information in this article is intended for educational/entertainment purposes only. This information should not be used as medical/therapeutic advice. Please seek a doctor/therapist for health advice.
Works cited:
[1] https://answersingenesis.org/genetics/dna-structure/dna-what-does-it-prove/
[2] https://www.focusonthefamily.com/faith/the-case-for-a-creator/
[3] https://www.americamagazine.org/magazine
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1298980/
[6] https://www.amazon.com/Fundamentals-General-Organic-Biological-Chemistry/dp/0134218329
[7] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203212/
[8] https://academic.oup.com/mbe/article/19/5/640/1067768
[9] https://www.nejm.org/doi/pdf/10.1056/NEJM197007162830313
[10] https://onlinelibrary.wiley.com/doi/abs/10.1002/evan.20266
[11] https://www.nejm.org/doi/pdf/10.1056/NEJM198707093170209